pharmacogenomics

Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin
In this work, we developed models to predict drug response in cancer patients using cell line models
Jean Berthelet, Momeneh Foroutan, Dharmesh D Bhuva, Holly J Whitfield, Farrah El-Saafin, Joseph Cursons, Antonin Serrano, Michal Merdas, Elgene Lim, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Matthias Ernst, Frédéric Hollande, Robin L Anderson, Bhupinder Pal, Belinda Yeo, Melissa J Davis, Delphine Merino
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Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma
Background: Medulloblastoma (MB) is the most common malignant paediatric brain tumour and a leading cause of cancer-related mortality …
Laura Genovesi, Amanda Millar, Elissa Tolson, Matthew Singleton, Emily Hassall, Marija Kojic, Caterina Brighi, Emily Girard, Clara Andradas, Mani Kuchibhotla, Dharmesh D Bhuva, Raelene Endersby, Nicholas G Gottardo, Anne Bernard, Christelle Adolphe, James M Olson, Melissa J Davis, Brandon J Wainwright
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Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma